Sequence exceprt from the human FoxP2 gene, implicated in language development
PCR has been the bedrock of molecular biology for decades. The premise is simple: with a few pieces of synthetic DNA called primers, and some clever manipulation of temperature, any genetic material can be copied a billion-fold: a single molecule of DNA can be magnified to detectable levels, unlocking diverse and powerful applications. Over 20 years of experimentation, we have developed state-of-the-art technologies for making PCR more economical, accessible, and accurate than ever before.
Multiplexing refers to the detection of multiple targets in a single PCR reaction: simple in principle, highly challenging in practice. TAAG’s answer to that challenge is Mila, a suite of advanced AI algorithms that selects the best possible set of primers and probes from billions of possibilities.
Streamline your PCR workflow with TAAG’s SPID format: 8-well PCR strips with attached or separate caps, preloaded with PCR mix. Master mix and primer mix are separated until loading using our proprietary partitioning technology.
Perform simultaneous detection and identification of over 50 organisms in a single PCR well and one fluorescence channel. TAAG’s high-resolution melt (HRM) signature technology uses broad-range PCR followed by HRM to generate distinct DNA melting curve patterns (“signatures”). Machine learning algorithms are then used to match the results to a library of experimentally determined signatures for known organisms.
Next-Generation Sequencing (NGS) is a broad term for technologies that enable efficient and accurate reading of the nucleotide code (the "sequence"). Although NGS can be performed directly on a sample, it is often necessary to first amplify the region of interest using PCR, as part of a step called "library preparation."
All organisms have a genetic fingerprint. Using PCR and NGS, we can simultaneously identify hundreds of microorganisms with unparalleled accuracy and throughput.
Sometimes it is not enough to simply read the genetic code. Molecular biology is powerful because it can generate vast quantities of data, but analyzing that data for actionable patterns is no easy task. Artificial Intelligence can bridge the gap.
The TAAG xpert Assistant (TxA) is an AI-powered web application capable of interpreting molecular assay results, analyzing data, performing LIMS functions, and optimizing microbiological environmental monitoring programs using predictive contamination tracking.
Before we can do any testing with DNA (or its close relative RNA), we have to extract and purify it from the sample (in this context called the "matrix"). For lack of a better metaphor, extraction could be conceptualized as genetic sunglasses, blocking out the noise from other compounds so we can read more clearly. We call this noise "inhibition." Sometimes, it can be a surprisingly formidable foe.
Purify high-quality nucleic acids from difficult, highly inhibitory matrices using TAAG’s magnetic bead extraction technology. Suitable for magnetic manipulation in high-throughput, automated extraction platforms.
TAAG’s proprietary Q-Bead technology uses engineered resin beads to capture PCR inhibitors, leaving high quality nucleic acids in the supernatant.