HRM SIGNATURE
Ultra-high multiplex microbial species identification
Think small. Very small. TAAG's HRM SIGNATURE Technology is a microbiology laboratory in the tip of a pencil. Identify targets from a growing database of over 100 bacteria and fungi, all in two PCR wells.
High-Resolution
Melting Curve Signatures interpreted by AI
High-Resolution Melting Curve analysis is a powerful method that examines the unique melting temperature patterns of DNA fragments to identify targets. Using the pattern-recognition abilities of artifical intelligence, we have developed a novel implementation of HRM for ultra-high multiplex target identification.
Multiplexing without probes for a fraction of the cost per reaction
TAAG's HRM Signature technology allows for the simultaneous detection of multiple targets per reaction, without the use of expensive hydrolysis probes.
Unique melting curves
interpreted by AI
Each target is identified using a distinctive melting curve "fingerprint" that is matched to our growing database of organisms by machine learning algorithms.
Add your custom targets to an ever-expanding library of organisms
We can experimentally fingerprint any bacterial or fungal species and add it to our database of organisms for detection.
High-Resolution
Melting Curve Signatures interpreted by AI
High-Resolution Melting Curve analysis is a powerful method that examines the unique melting temperature patterns of DNA fragments to identify targets. Using the pattern-recognition abilities of artifical intelligence, we have developed a novel implementation of HRM for ultra-high multiplex target identification.
Multiplexing without probes for a fraction of the cost per reaction
TAAG's HRM Signature technology allows for the simultaneous detection of multiple targets per reaction, without the use of expensive hydrolysis probes.
Unique melting curves
interpreted by AI
Each target is identified using a distinctive melting curve "fingerprint" that is matched to our growing database of organisms by machine learning algorithms.
Add your custom targets to an ever-expanding library of organisms
We can experimentally fingerprint any bacterial or fungal species and add it to our database of organisms for detection.
Differentiate between over
50 targets in a single PCR reaction
How it works
The target is amplified by broad-range PCR (also known as universal PCR) in a way that generates a mixture of fragments with different melting temperatures.
The reaction temperature is slowly increased while recording fluorescence to generate a high-resolution melt “signature”.
TxA’s artificial intelligence matches curves to a library of experimentally determined patterns for organisms of interest.
Comparison of TAAG HRM Signature With Other
High-Multiplex Microbial Identification Methods
